Owner of a Lonely Heart

Overview

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

Guest Stars

Curtis Armstrong

Robert Martin

Rosanna Arquette

Constance Ferguson

Timothy Bottoms

Carl Murphy

Patricia Bethune

Nurse Ginger

Margaret Welsh

Dorie Russell

Pat Healy

Tom Russell

Elaine Kao

NICU Nurse

Sarah Utterback

Olivia Harper